Gly-CRRET Laboratory :

Growth, Repairing and Regeneration of Tissues

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Weibel-Palade bodies orchestrate pericytes during angiogenesis

08/08/2019 - This study performed at CRRET laboratory and published in the journal ATVB demonstrated that WPB Weibel-Palade bodies (WPBs) exocytosis and Ang-2 secretion are regulated during angiogenesis to limit pericyte coverage of remodeling vessels by disrupting Ang-1/Tie2 autocrine signaling in pericytes.
Weibel-Palade bodies are endothelial cell (EC)-specific storage organelles formed by vWF (von Willebrand factor) polymerization and that contain the proangiogenic factor Ang-2 (...)

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Multivalent Pseudopeptides Targeting Cell Surface Nucleoproteins Inhibit Cancer Cell Invasion through Tissue Inhibitor of Metalloproteinases 3 (TIMP-3) Release

18/01/2013 - Previously, we have demonstrated that the synthetic multivalent pseudopeptides named NucAnts, targeting the surface nucleolin, inhibit angiogenesis and tumor growth (Destouches et al., 2008, PLoS ONE ; Destouches et al., 2011, (...)

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Antitumor and angiostatic activities of the antimicrobial peptide dermaseptin b2

19/11/2012 - Recently, we have found that the skin secretions of the Amazonian tree frog Phyllomedusa bicolor genus contains molecules with antitumor and angiostatic activities (van Zoggel et al. (2012) Amino Acids 42: 385-395). We identified (...)

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Director:

Dulcé Papy-Garcia

papy@u-pec.fr

Address :

Laboratoire CRRET

Université Paris Est Créteil Val de Marne, 61 avenue du Général de Gaulle

94010 Créteil Cedex

Secretariat :

Sarah Laroussi

laroussi@u-pec.fr

tel : +33(0)145177080

fax : +33(0)145171816

Access maps :

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