Gly-CRRET Laboratory :

Growth, Repairing and Regeneration of Tissues


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Weibel-Palade bodies orchestrate pericytes during angiogenesis

08/08/2019 - This study performed at CRRET laboratory and published in the journal ATVB demonstrated that WPB Weibel-Palade bodies (WPBs) exocytosis and Ang-2 secretion are regulated during angiogenesis to limit pericyte coverage of remodeling vessels by disrupting Ang-1/Tie2 autocrine signaling in pericytes.
Weibel-Palade bodies are endothelial cell (EC)-specific storage organelles formed by vWF (von Willebrand factor) polymerization and that contain the proangiogenic factor Ang-2 (...)

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Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters in vitro synaptic structural matching and exaggerates protein synthesis .

05/09/2017 - En2 is a gene of susceptibility to autism and people with autism display an overexpression of En2 protein, but the effects of this overexpression are not known. Automatic detection and analysis of synaptic junctions areas. Details (...)

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The CRRET (UPEC) leader of the project “ArrestAD” for the European program H2020 Novel Ideas for Radically New Technologies

03/03/2017 - The European “ArrestAD” project, coordinate by the CRRET laboratory and targeting Alzheimer disease, has been selected with the highest evaluation score under the European Program for Research and Innovation “H2020 FET-OPEN Novel Ideas (...)

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Dulcé Papy-Garcia

Address :

Laboratoire CRRET

Université Paris Est Créteil Val de Marne, 61 avenue du Général de Gaulle

94010 Créteil Cedex

Secretariat :

Sarah Laroussi

tel : +33(0)145177080

fax : +33(0)145171816

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