Gly-CRRET Laboratory :

Growth, Repairing and Regeneration of Tissues


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Weibel-Palade bodies orchestrate pericytes during angiogenesis

08/08/2019 - This study performed at CRRET laboratory and published in the journal ATVB demonstrated that WPB Weibel-Palade bodies (WPBs) exocytosis and Ang-2 secretion are regulated during angiogenesis to limit pericyte coverage of remodeling vessels by disrupting Ang-1/Tie2 autocrine signaling in pericytes.
Weibel-Palade bodies are endothelial cell (EC)-specific storage organelles formed by vWF (von Willebrand factor) polymerization and that contain the proangiogenic factor Ang-2 (...)

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Glycosaminoglycan mimetics potentiate stem cells properties: a new hope for the optimization of cell therapy products

02/11/2011 - Successful use of mesenchymal stem cell (MSC)-based therapeutic products is conditioned by transplantation of optimized cells in permissive microenvironment. Mesenchymal stem cell (MSC) fates are tightly regulated by humoral (...)

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Alterations of overused supraspinatus tendon: A possible role of glycosaminoglycans and HARP/pleiotrophin in early tendon pathology

27/06/2011 - Supraspinatus tendon overuse injuries lead to significant pain and disability in athletes and workers. Despite the prevalence and high social cost of these injuries, the early pathological events are not well known. GAGs labelled (...)

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Dulcé Papy-Garcia

Address :

Laboratoire CRRET

Université Paris Est Créteil Val de Marne, 61 avenue du Général de Gaulle

94010 Créteil Cedex

Secretariat :

Sarah Laroussi

tel : +33(0)145177080

fax : +33(0)145171816

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