Gly-CRRET Laboratory :

Growth, Repairing and Regeneration of Tissues

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Weibel-Palade bodies orchestrate pericytes during angiogenesis

08/08/2019 - This study performed at CRRET laboratory and published in the journal ATVB demonstrated that WPB Weibel-Palade bodies (WPBs) exocytosis and Ang-2 secretion are regulated during angiogenesis to limit pericyte coverage of remodeling vessels by disrupting Ang-1/Tie2 autocrine signaling in pericytes.
Weibel-Palade bodies are endothelial cell (EC)-specific storage organelles formed by vWF (von Willebrand factor) polymerization and that contain the proangiogenic factor Ang-2 (...)

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News

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Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer

31/05/2016 - The study participates to the molecular understanding of the mechanisms involved in prostate cancer progression and to the research of new treatment options for its advanced forms. Despite the advent of several new treatment options (...)

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A fine structural modification of glycosaminoglycans is correlated with the progression of muscle regeneration after ischemia: toward a matrix-based therapy?

29/10/2015 - Critical limb ischaemia often leads to amputation of the limb and potential mortality. The OTR-GAG mimetic treatment improves muscle repair as soon as day 8 after ischaemia, by increasing the neoformation of blood vessels. (...)

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Director:

Dulcé Papy-Garcia

papy@u-pec.fr

Address :

Laboratoire CRRET

Université Paris Est Créteil Val de Marne, 61 avenue du Général de Gaulle

94010 Créteil Cedex

Secretariat :

Sarah Laroussi

laroussi@u-pec.fr

tel : +33(0)145177080

fax : +33(0)145171816

Access maps :

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