Gly-CRRET Laboratory :

Growth, Repairing and Regeneration of Tissues

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Weibel-Palade bodies orchestrate pericytes during angiogenesis

08/08/2019 - This study performed at CRRET laboratory and published in the journal ATVB demonstrated that WPB Weibel-Palade bodies (WPBs) exocytosis and Ang-2 secretion are regulated during angiogenesis to limit pericyte coverage of remodeling vessels by disrupting Ang-1/Tie2 autocrine signaling in pericytes.
Weibel-Palade bodies are endothelial cell (EC)-specific storage organelles formed by vWF (von Willebrand factor) polymerization and that contain the proangiogenic factor Ang-2 (...)

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News

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Heparanase and Syndecan-4 are involved in Low Molecular Weight Fucoidan-induced angiogenesis.

10/12/2015 - Induction of angiogenesis is a potential treatment for chronic ischemia. Low molecular weight fucoidan (LMWF), the sulfated polysaccharide from brown seaweeds, has been shown to promote revascularization in a rat limb ischemia, (...)

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Pleiotrophin exerts its migration and invasion effect through the neuropilin-1 pathway

29/09/2015 - The study described in this article participates to the understanding of the role and the mechanisms of the pleiotrophin in tumor growth and associated angiogenesis. PC3 cells exhibiting NRP-1 labeling (fire LUT) and nuclear DNA (...)

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Director:

Dulcé Papy-Garcia

papy@u-pec.fr

Address :

Laboratoire CRRET

Université Paris Est Créteil Val de Marne, 61 avenue du Général de Gaulle

94010 Créteil Cedex

Secretariat :

Sarah Laroussi

laroussi@u-pec.fr

tel : +33(0)145177080

fax : +33(0)145171816

Access maps :

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